STUDY OF NOVEL CHEMILUMINESCENT SYSTEMS AND ELABORATION OF THEIR APPLICATIONS ON THE DEVELOPMENT OF NEW AUTOMATED ANALYTICAL METHODS FOR THE DETERMINATION OF FOOD CONSTITUENTS, ENVIRONMENTAL POLLUTANTS AND ACTIVE PHARMACEUTICAL COMPOUNDS

Abstract: 

LUMEN (Latin: Light), used as project acronym, is the SI unit that measures the perceived power of light and encapsulates the overall gist of the proposal in a single word; that is the emission of light, generated from chemical reactions, in chemical terminology known as chemiluminescence (CL). During the past two decades chemiluminescence has attracted the interest of analytical chemists and despite its distinct advantages (high sensitivity, low cost instrumentation) the applications of CL in routine and in field (in-situ) analysis are limited.

The aim of this project is to provide an interdisciplinary approach to the analytical utility of CL detection by revisiting its limitations and introducing novel research approaches.

More specifically this project aims to:

  1. the enhancement of CL sensitivity by synthesizing and testing novel CL reagents and new catalysts;
  2. the amendment of CL selectivity by employing molecular imprinted polymers, solvent pre-oxidation CL (SPOC) and synthetic bilayer membranes (vesicles);
  3. the establishment of generic principles concerning CL reactions and their response to various compounds and sample matrices;
  4. the development and validation of automated low cost CL methods for the determination of food constituents, environmental pollutants and active pharmaceutical compounds in food, environmental, pharmaceutical and biological samples;
  5. the establishment of a collaboration network between Greek research teams that excel in the field of chemiluminescence, and the training of new researchers.

The implementation of the project will deliver significant new findings in the field of chemiluminescence which will expand its applications in analytical chemistry mainly in routine and field analysis.

Validated analytical protocols and in situ analysis kits for specific compounds or as total analysis systems (TAS) will be prepared and optimally utilized in quality control for research and industrial applications.

MIS:  375723

Project info

Acronym:
LUMEN
Coordinating Institution:
University of Ioannina
Scientific Coordinator:
Vlessidis Athanasios
Research Team 2 Leader:
Calokerinos Antony
Research Team 3 Leader:
Papadopoulos Kyriakos
Research Team 4 Leader:
Koupparis Michael

Stats

I.D.:
104
Mis:
375723
Duration (months):
40
Budget:
584 775.00
Diavgeia:
ΑΔΑ: Β49Θ9-ΔΣ4

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